Studies on hindered phenols and analogs. 2. 1, 3-Benzoxathioles having SRS-A inhibiting activity

…, T Kanai, K Hasegawa, T Yamaguchi…

Index: Aizawa, Yuichi; Kanai, Tsutomu; Hasegawa, Kazuo; Yamaguchi, Takeshi; Iizuka, Yoshio; et al. Journal of Medicinal Chemistry, 1990 , vol. 33, # 5 p. 1491 - 1496

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Citation Number: 20

Abstract

Studies on hindered phenols (TH) have caused great development in the field of antioxidants for polymers.'It has been well-known that phenols (TH), eg, 2, g-di-tertbutyl-4- methylphenol (BHT, l), play the role of scavengers for the ROO'radical as shown in Chart I, in which RH and X'are unsaturated hydrocarbons and initiators such as active oxygen species, respectively. Also, in vivo studies have demonstrated that the active-oxygen species ...