Synthesis of 3??tert??aminothiophens and their tetrahydro derivatives via enamines

FA Buiter, JH Weiland…

Index: Buiter,F.A. et al. Recueil des Travaux Chimiques des Pays-Bas, 1964 , vol. 83, p. 1160 - 1168

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Citation Number: 18

Abstract

Abstract Aromatization of 3-ketotetrahydrothiophen enamines (II) furnishes 3-dialkyl- aminothiophens (III). Reduction of the enamines with formic acid yields the tetrahydro derivatives (V). These compounds represent the first examples of simple 3-tert-amino- thiophens and-tetrahydrothiophens.

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