Organic letters

Palladium-Catalyzed sp 2 and sp 3 C–H Bond Activation and Addition to Isatin toward 3-Hydroxy-2-oxindoles

GW Wang, AX Zhou, JJ Wang, RB Hu, SD Yang

Index: Wu, Ge; Zhou, Jun; Zhang, Min; Hu, Peng; Su, Weiping Chemical Communications, 2012 , vol. 48, # 71 p. 8964 - 8966

Full Text: HTML

Citation Number: 30

Abstract

The first Pd (II)-catalyzed C–H addition to isatins by direct sp 2/sp 3 C–H bond activation for the construction of 3-substituted-3-hydroxy-2-oxindoles is reported. The bidentate nitrogen ligands were found to promote this reaction. Specifically, the preliminary bioassay indicated

Related Articles:

An Efficient Synthesis of 2??Substituted Benzoxazoles via RuCl3· 3H2O Catalyzed Tandem Reactions in Ionic Liquid

[Fan, Xuesen; He, Yan; Wang, Yangyang; Zhang, Xinying; Wang, Jianji Chinese Journal of Chemistry, 2011 , vol. 29, # 4 p. 773 - 777]

Direct arylation of benzoxazole C–H bonds with iodobenzene diacetates

[Yu, Peng; Zhang, Guangyou; Chen, Fan; Cheng, Jiang Tetrahedron Letters, 2012 , vol. 53, # 34 p. 4588 - 4590]

Copper-catalyzed synthesis of benzoxazoles via a regioselective C− H functionalization/C− O bond formation under an air atmosphere

[Ueda, Satoshi; Nagasawa, Hideko Journal of Organic Chemistry, 2009 , vol. 74, # 11 p. 4272 - 4277]

Iron-catalyzed 2-arylbenzoxazole formation from o-nitrophenols and benzylic alcohols

[Wu, Mingyue; Hu, Xiong; Liu, Juan; Liao, Yunfeng; Deng, Guo-Jun Organic Letters, 2012 , vol. 14, # 11 p. 2722 - 2725]

Synthesis of 2??Arylbenzoxazoles through Oxidation of C–H Bonds Adjacent to Oxygen Atoms

[Gu, Lijun; Wang, Wei; Xiong, Yong; Huang, Xiangzhong; Li, Ganpeng European Journal of Organic Chemistry, 2014 , vol. 2014, # 2 p. 319 - 322]

More Articles...