Use of metal complexation in the synthesis of medium-ring acetylenic lactones

SD Najdi, MM Olmstead, NE Schore

Index: Najdi, Samir D.; Olmstead, Marilyn M.; Schore, Neil E. Journal of Organometallic Chemistry, 1992 , vol. 431, # 3 p. 335 - 358

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Citation Number: 26

Abstract

Abstract The hexacarbonyldicobalt complexes of several appropriately designed acetylenic lactone precursors have been prepared, and lactones containing Co 2 (CO) 6-complexed triple bonds in seven-, ten-, and eleven-membered rings obtained. The latter were best obtained through a retro-Dieckmann fragmentation of 2-(hydroxybutynyl) derivatives of 1, 3- clohexanedione. Attempts to extend this reaction to cyclohexanones bearing other anion- ...