An improved procedure for efficient generation of methyl (or p-tolyl) thiomethyl Grignard reagent and its use in organic syntheses.

K Ogura, M Fujita, K Takahashi, H Iida

Index: Ogura, Katsuyuki; Fujita, Makoto; Takahashi, Kazumasa; Iida, Hirotada Chemistry Letters, 1982 , p. 1697 - 1698

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Citation Number: 7

Abstract

The optimal conditions for transformation of a chloromethyl sulfide into the corresponding Grignard reagent (2) in a high yield are established and (2) is shown to react with various functional groups such as an alkyl halide, an aldehyde, and a sulfinic ester, revealing its usefulness in organic syntheses.