Journal of heterocyclic chemistry

N??1 Substituted ethyl 4??pyrazolecarboxylates: Synthesis and spectroscopic investigations

W Holzer, G Seiringer

Index: Holzer, Wolfgang; Seiringer, Gertrud Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 4 p. 865 - 872

Full Text: HTML

Citation Number: 23

Abstract

Abstract The synthesis of various N-1 substituted ethyl 4-pyrazolecarboxylates via reaction of ethyl 2-formyl-3-oxo-propionate (= ethoxycarbonylmalondialdehyde) with appropriately substituted hydrazines is described. Moreover, detailed nmr-spectroscopic investigations with the title compounds are presented.

Related Articles:

Nonaqueous diazotization of 5??amino??1??aryl??1H??pyrazole??4??carboxylate esters

[Beck, James R.; Gajewski, Robert P.; Lynch, Michael P.; Wright, Fred L. Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 267 - 270]

Synthesis and structure–activity relationships of 1-phenylpyrazoles as xanthine oxidase inhibitors

[Ishibuchi, Seigo; Morimoto, Hiroshi; Oe, Takanori; Ikebe, Tsuguo; Inoue, Hiroyoshi; Fukunari, Atsushi; Kamezawa, Miho; Yamada, Ichimaro; Naka, Yoichi Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 7 p. 879 - 882]

Synthesis and structure–activity relationships of 1-phenylpyrazoles as xanthine oxidase inhibitors

[Ishibuchi, Seigo; Morimoto, Hiroshi; Oe, Takanori; Ikebe, Tsuguo; Inoue, Hiroyoshi; Fukunari, Atsushi; Kamezawa, Miho; Yamada, Ichimaro; Naka, Yoichi Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 7 p. 879 - 882]

Synthesis and structure–activity relationships of 1-phenylpyrazoles as xanthine oxidase inhibitors

[Ishibuchi, Seigo; Morimoto, Hiroshi; Oe, Takanori; Ikebe, Tsuguo; Inoue, Hiroyoshi; Fukunari, Atsushi; Kamezawa, Miho; Yamada, Ichimaro; Naka, Yoichi Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 7 p. 879 - 882]

More Articles...