Mild and efficient synthesis of thiocarbonates and thiocarbamates via a three-component coupling utilizing Cs 2 CO 3 and TBAI

RN Salvatore, S Sahab, KW Jung

Index: Salvatore, Ralph N.; Sahab, Suma; Jung, Kyung Woon Tetrahedron Letters, 2001 , vol. 42, # 11 p. 2055 - 2058

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Citation Number: 64

Abstract

The presence of cesium carbonate and tetrabutylammonium iodide (TBAI) facilitated efficient thiocarbonylation of alcohols, and thiocarbamation of amines, using carbon disulfide with alkyl halides. This protocol was mild, chemoselective, and efficient, compared to the existing methods.