The chemistry of vicinal tricarbonyls. A stable vinyl tricarbonyl hydrate as a di-and trielectrophile

…, J Fukuyama, N Murugesan, J Van Duzer…

Index: Wasserman, Harry H.; Fukuyama, James; Murugesan, Natesan; Duzer, John van; Lombardo, Louis; et al. Journal of the American Chemical Society, 1989 , vol. 111, # 1 p. 371 - 372

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Citation Number: 48

Abstract

The greatly enhanced reactivity of the central carbonyl of a 1, 2, 3-tricarbonyl grouping has long been recognized among organic chemists, but little application has been made of this functional unit in synthetic operations.'We have recently demonstrated the advantages of this highly electrophilic system in the fusion of p-lactam nuclei to the five-and six-membered rings of carbacepham, carbapenam, and penam We now report methods for the formation ...