Synthetic Communications

Chlorotrimethylsilane: A Powerful Lewis Acidic Catalyst in Michael??Type Friedel–Crafts Reactions of Indoles and Enones

LW Xu, W Zhou, L Yang, CG Xia

Index: Xu, Li-Wen; Zhou, Wei; Yang, Lei; Xia, Chun-Gu Synthetic Communications, 2007 , vol. 37, # 18 p. 3095 - 3104

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Citation Number: 9

Abstract

Abstract Catalytic amount of chlorotrimethylsilane (TMSCl) was found to be an effective silicon Lewis acid catalyst in catalyzing the Michael??type Friedel–Crafts reactions of indoles and chalcones to afford corresponding 3??substituted indole derivatives in good to excellent

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