Total synthesis of carbazomycin G

S Chakraborty, C Saha

Index: Chakraborty, Suchandra; Saha, Chandan European Journal of Organic Chemistry, 2013 , # 25 p. 5731 - 5736

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Citation Number: 3

Abstract

Abstract A concise total synthesis of carbazomycin G has been completed in five steps. Cerium (IV) ammonium nitrate (CAN)–SiO 2-mediated oxidation of 2-methyl-2, 3, 4, 9- tetrahydro-1H-carbazol-1-one afforded a carbazole-1, 4-quinone derivative, 2-methyl-1H- carbazole-1, 4 (9H)-dione, the synthetic precusor, which on, which, on Thiele acetylation under newly developed HBF 4 catalysis conditions, yielded 4-hydroxy-2-methyl-9H- ...