Synthesis of 2-phenylthiazolidine derivatives as cardiotonic agents. V. Modification of the thiazolidine moiety of 2-(phenylpiperazinylalkoxyphenyl) thiazolidine-3- …

H NATE, Y SEKINE, K ODA, K AOE, H NAKAI…

Index: Chemical and Pharmaceutical Bulletin, , vol. 35, # 8 p. 3253 - 3261

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Abstract

... 3255 Chemistry Synthesis of the pyrrolidine analogue (2) was carried out through the sequence of reactions outlined in Chart 2. Reaction of the benzaldehyde (4)3) with morpholine and potassium cyanide gave the aminonitrile (5). Cyanoethylation of 5 followed by ... Vol. 35 (1987 ...