Silica-supported perchloric acid (HClO4–SiO2): a mild, reusable and highly efficient heterogeneous catalyst for multicomponent synthesis of 1, 4-dihydropyridines via …

SS Mansoor, K Aswin, K Logaiya, PN Sudhan…

Index: Mansoor, Syed Sheik; Aswin, Krishnamoorthy; Logaiya, Kuppan; Sudhan, Prasanna Nitiya; Malik, Saleem Research on Chemical Intermediates, 2014 , vol. 40, # 1 p. 357 - 369

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Citation Number: 11

Abstract

Abstract Facile synthesis of some 1, 4-dihydropyridine derivatives via Hantzsch reaction of 5, 5-dimethyl-1, 3-cyclohexanedione (dimedone), 1, 3-diphenyl-2-propen-1-one derivatives and ammonium acetate under solvent-free condition in the presence of silica-supported perchloric acid (HClO 4–SiO 2) is described. The catalyst is easily prepared, stable, reusable and efficient under the reaction conditions.