Synlett

Direct preparation of benzofurans from O-arylhydroxylamines

…, KM Jones, EA Matts, A Porzelle, NCO Tomkinson

Index: Contiero, Fanny; Jones, Kevin M.; Matts, Edward A.; Porzelle, Achim; Tomkinson, Nicholas C.O. Synlett, 2009 , # 18 p. 3003 - 3006

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Citation Number: 14

Abstract

Abstract Reaction of O-arylhydroxylamine hydrochlorides with either cyclic or acyclic ketones in the presence of methanesulfonic acid leads directly to the benzofuran derivative via a proposed one-pot condensation-rearrangement-cyclisation reaction sequence in good to excellent yields.

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