Preparation of new monomers aza-β 3-aminoacids for solid-phase syntheses of aza-β 3-peptides

O Busnel, M Baudy-Floc'h

Index: Busnel, Olivier; Baudy-Floc'h, Michele Tetrahedron Letters, 2007 , vol. 48, # 33 p. 5767 - 5770

Full Text: HTML

Citation Number: 22

Abstract

For our ongoing projects on the synthesis of aza-β 3 -peptides, we need to have ample access to the aza-β 3 -amino acid building blocks with proteinogenic side chains and N β -Fmoc protection. With the exceptions of aza-β 3 -Lys, aza-β 3 -Tyr, aza-β 3 -Arg only Fmoc-protected aza-β 3 -amino acids with nonfunctionalized and achiral side chains have been published. 10 We described here, in detail, the preparation of five new aza-β 3 -amino acid derivatives, ...