Highly chemo-and regio-selective hydroxylations of o-and m-substituted toluenes to benzyl alcohols with Cellulosimicrobium cellulans EB-8-4

S Dai, J Wu, Z Wang, Y Chen, Z Li

Index: Dai, Shiyao; Wu, Jinchuan; Wang, Zunsheng; Chen, Yongzheng; Li, Zhi Tetrahedron, 2010 , vol. 66, # 34 p. 6919 - 6923

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Abstract

Highly chemo-and regio-selective benzylic hydroxylations of o-and m-substituted toluenes were achieved with the easily available and easy-to-handle resting cells of Cellulosimicrobium cellulans EB-8-4 as biocatalysts, giving the corresponding benzyl alcohols as single product. Benzyl alcohols were obtained in 78–94% yield, demonstrating the first green, clean, and simple method for the preparation of benzyl alcohols via ...