Transformations of gem-Dichloroarylcyclopropanes in the Reaction with NOCl· 2SO3. Synthesis of 3-Aryl-5-chloroisoxazoles

OB Bondarenko, AY Gavrilova, DS Murodov…

Index: Bondarenko; Gavrilova; Murodov; Zefirov; Zyk Russian Journal of Organic Chemistry, 2013 , vol. 49, # 2 p. 186 - 194 Zh. Org. Khim., 2013 , vol. 49, # 2 p. 198 - 206,9

Full Text: HTML

Citation Number: 4

Abstract

Abstract Nitrosation with complex NOCl· 2SO 3 of gem-dichloroarylcyclopropanes containing acceptor substituents in the aromatic ring proceeded chemo-and regioselectively affording 3-aryl-5-chloroisoxazoles in high yields. The presence of donor substituents complicated the reaction by the occurrence of competing processes.