Tetrahedron letters

Fluorinated vinyl carbamates and carbamoyloxy allylsilanes. α-Metalation, organolithium addition-elimination, and fluoride. Mediated electrophilic reactivity patterns

J Lee, M Tsukazaki, V Snieckus

Index: Lee, John; Tsukazaki, Masao; Snieckus, Victor Tetrahedron Letters, 1993 , vol. 34, # 3 p. 415 - 418

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Citation Number: 49

Abstract

Abstract LiTMP or LDA-mediated in situ generation of α-lithio difluorovinyl carbamate1b allows the preparation of silylated derivatives4a and2b which undergo organolithium addition-elimination and fluoride-mediated condensation reactions respectively to give new functionalized organofluorine derivatives5a–d (Table 2) and11a-c (Table 3).