Synthesis

A convenient trifluoroacetylation reagent: N-(Trifluoroacetyl) succinimide

AR Katritzky, B Yang, G Qiu, Z Zhang

Index: Katritzky, Alan R.; Yang, Baozhen; Guofang, Qiu; Zhang, Zhongxing Synthesis, 1999 , # 1 p. 55 - 57

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Citation Number: 13

Abstract

Abstract: N-(Trifluoroacetyl) succinimide, easily prepared from trifluoroacetic anhydride and succinimide forms a novel, convenient trifluoroacetylating reagent. It trifluoroacetylates alcohols, phenols and amines, to generate trifluoroacetate esters, and trifluoroacetamides in excellent yields with very efficient work up procedures. Key words: N-(trifluoroacetyl) succinimide, trifluoroacetylating reagent, trifluoroacetate esters, trifluoroacetamides

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