Synthesis and biological activity of β-acylhydrazides of aroylpyruvic acids

VO Koz'minykh, NM Igidov, VI Il'enko…

Index: Koz'minykh, V. O.; Igidov, N. M.; Il'enko, V. I.; Milyutin, A. V.; Kolla, V. E.; et al. Pharmaceutical Chemistry Journal, 1992 , vol. 26, # 7 p. 575 - 579 Khimiko-Farmatsevticheskii Zhurnal, 1992 , vol. 26, # 7-8 p. 28 - 31

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Abstract

It was established earlier that amides of aroylpyruvic acids are characterized by a wide spectrum of biological actions, including antimicrobial [4], anti-inflammatory [i, 2], analgetic [i], and antispasmodic [5] activity. These compounds may also be used as intermediate materials for the synthesis of dyes, pesticides, and various other nitrogen-containing biologically-active compounds [3]. The structurally-related $-benzoylpyruvoylhydrazide of ...