Tetrahedron Letters

One-pot and microwave-assisted synthesis of N-sulfonylaziridines

H Xu, H Tian, L Zheng, Q Liu, L Wang, S Zhang

Index: Xu, Hao; Tian, Hua; Zheng, Liangyu; Liu, Qingwen; Wang, Li; Zhang, Suoqin Tetrahedron Letters, 2011 , vol. 52, # 22 p. 2873 - 2875

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Citation Number: 3

Abstract

Abstract A novel and efficient microwave-assisted one-step reaction was developed to synthesize chiral N-sulfonylaziridines by the reaction of different chiral amino alcohols and sulfonic chlorides. The newly developed microwave synthetic method has the advantage of reducing the reaction time from 24 to 0.5 h with improved yields (84–93%) and minimizing by-products.

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