A DMAP-Catalyzed Approach to the Industrial-Scale Preparation of N-6-Demethylated 9, 10-Dihydrolysergic Acid Methyl Ester: A Key Cabergoline and Pergolide …

Z Časar, T Mesar

Index: Kok, Gaik B.; Pye, Cory C.; Singer, Robert D.; Scammells, Peter J. Journal of Organic Chemistry, 2010 , vol. 75, # 14 p. 4806 - 4811

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Abstract

... Select a Journal or Book ... figure Scheme 1. Syntheses of cabergoline and pergolide together with the structure of their key precursors: ergoline skeleton, d-lysergic acid amides, ergocryptine ... entry, type and scale of reaction, additive, reaction time [h], yield [%] b, 2:1 molar ratio. ...