Monoacylaminals by the benzotriazole-assisted aminoalkylation of amides

AR Katritzky, CN Fali, W Bao, M Qi

Index: Katritzky, Alan R.; Fali, Clara N.; Bao, Weiliang; Qi, Ming Synthesis, 1998 , # 10 p. 1421 - 1423

Full Text: HTML

Citation Number: 8

Abstract

Abstract: A general synthesis of a range of monoacylaminals from the reaction of N-(α- aminoalkyl) benzotriazoles with amides in the presence of a base has been developed. In less reactive cases zinc bromide was used to facilitate the above reaction. Key words: monoacylaminal, aminoalkylation, amide, benzotriazole, amine