Resorcin [4] arene??Derived Mono??and Diphosphines in Suzuki Cross??Coupling

H El Moll, D Sémeril, D Matt…

Index: Moll, Hani El; Semeril, David; Matt, Dominique; Toupet, Loic Advanced Synthesis and Catalysis, 2010 , vol. 352, # 5 p. 901 - 908

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Citation Number: 12

Abstract

Abstract Three resorcin [4] arene cavitands (1–3) having either one or two resorcinolic C-2 atoms substituted by a [BOND] CH 2 PPh 2 podand arm were assessed in the Suzuki arylation of aryl bromides with phenylboronic acid. Using P: Pd ratios of 2: 1 and operating in dioxane at 100 C with a catalyst loading of 0.001 mol% resulted in highly efficient catalytic systems. For example, TOFs up to 34570 mol (converted ArBr)⋅ mol (Pd)− 1⋅ h− 1 were ...