Ecofriendly fast batch synthesis of dioxolanes, dithiolanes, and oxathiolanes without solvent under microwave irradiation

B Perio, MJ Dozias, J Hamelin

Index: Perio, Bertrand; Dozias, Marie-Joelle; Hamelin, Jack Organic Process Research and Development, 1998 , vol. 2, # 6 p. 428 - 430

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Citation Number: 48

Abstract

2, 2-Dimethoxypropane and 3, 3-dimethoxypentane react with 1, 2-ethanediol, thio, and oxathio analogues to give the corresponding protected carbonyls in high yield under mild solvent-free conditions. These environmentally benign conditions under microwave irradiation are applied to a large-scale synthesis.