Amidoselenation of olefins and its utilization for synthesis of allylic amides

…, T Aoai, H Owada, S Uemura, M Okano

Index: Toshimitsu, Akio; Aoai, Toshiaki; Owada, Hiroto; Uemura, Sakae; Okano, Masaya Journal of Organic Chemistry, 1981 , vol. 46, # 23 p. 4727 - 4733

Full Text: HTML

Citation Number: 52

Abstract

The reaction of phenylselenyl chloride with olefins in acetonitrile containing trifluoromethanesulfonic acid and water affords P-acetamidoalkyl phenyl selenides in good to excellent yields. This represents the fit example of one-pot amidoselenation of mono-and disubstituted olefins. The reaction can be carried out in benzonitrile, propionitrile, butyronitrile, or ethyl cyanoacetate. It was confirmed that the amidoselenation reaction ...