Scaling up of dihydropyridine ester synthesis by using aqueous hydrotrope solutions in a continuous microwave reactor

BM Khadilkar, VR Madyar

Index: Khadilkar, Bhushan M.; Madyar, Virendra R. Synthetic Communications, 1999 , vol. 29, # 7 p. 1195 - 1200

Full Text: HTML

Citation Number: 59

Abstract

We report here the scaling up of clinically important dihydropyridine by using a continuous microwave reactor (CMR). We also report the use of aqueous hydrotrope solution as a cheap, safe and “green” alternative to organic solvent to carry out homogeneous reactions

Related Articles:

Reactivity of aromatic o-hydroxy oximes. I. Synthesis and aminolysis of acylglycine esters of aromatic o-hydroxy oximes.

[Hayashi, Ikuo; Ogihara, Keizo; Shimizu, Kiyoshi Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 8 p. 2432 - 2437]

Hydroxylation of nitroarenes with alkyl hydroperoxide anions via vicarious nucleophilic substitution of hydrogen

[Makosza, Mieczyslaw; Sienkiewicz, Krzysztof Journal of Organic Chemistry, 1998 , vol. 63, # 13 p. 4199 - 4208]

Vicarious nucleophilic hydroxylation of aromatic nitro compounds with organic hydroperoxides

[Brose, Thomas; Holzscheiter, Felix; Mattersteig, Gunter; Pritzkow, Wilhelm; Voerckel, Volkmar Journal fuer Praktische Chemie/Chemiker-Zeitung, 1992 , vol. 334, # 6 p. 497 - 504]

One??Step Reaction of Friedel–Crafts Acylation and Demethylation of Aryl??Methyl Ethers Catalyzed by Ytterbium (III) Triflate

[Su, Weike; Jin, Can Synthetic Communications, 2004 , vol. 34, # 22 p. 4199 - 4205]

Preparation of hydroxybenzophenones using silica-gel supported ferric chloride

[Bendale, Pravin M.; Khadilkar, Bhushan M. Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 8 p. 1738 - 1739]

More Articles...