Nature Medicine 2017-11-20

Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow

Emily Bowers, Anastasiya Slaughter, Paul S Frenette, Rork Kuick, Oscar M Pello, Daniel Lucas

Index: 10.1038/nm.4448

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Abstract

Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow, Published online: 20 November 2017; doi:10.1038/nm.4448In the bone marrow, granulocyte-derived TNFα acts on endothelial cells to maintain the vasculature under steady-state conditions and to promote its regeneration after injury or transplantation.

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