Organic letters

Simple and one-pot protocol for synthesis of indene-spiro-oxindoles involving tandem Prins and Friedel-Crafts reactions

D Basavaiah, KR Reddy

Index: Basavaiah, Deevi; Reddy, Kanumuri Ramesh Organic Letters, 2007 , vol. 9, # 1 p. 57 - 60

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Citation Number: 93

Abstract

A simple and one-pot protocol for the synthesis of indene-spiro-oxindole derivatives via TiCl4-mediated reaction between 1, 1-diarylethylenes and isatin derivatives involving construction of two carbon-carbon bonds through tandem Prins and intramolecular Friedel- Crafts (PFC) reactions has been described. A plausible mechanism for this transformation is also presented.

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