Helvetica Chimica Acta

Nucleotides, Part LXV, Synthesis of 2′??Deoxyribonucleoside 5′??Phosphoramidites: New Building Blocks for the Inverse (5′??3′)??Oligonucleotide Approach

T Wagner, W Pfleiderer

Index: Wagner, Thomas; Pfleiderer, Wolfgang Helvetica Chimica Acta, 2000 , vol. 83, # 8 p. 2023 - 2035

Full Text: HTML

Citation Number: 19

Abstract

Abstract The syntheses of the 3′-O-(4, 4′-dimethoxytrityl)-protected 5′-phosphoramidites 25–28 and 5′-(hydrogen succinates) 29–32, which can be used as monomeric building blocks for the inverse (5′-3′)-oligodeoxyribonucleotide synthesis are described (Scheme). These activated nucleosides and nucleotides were obtained by two slightly different four-step syntheses starting with the base-protected nucleosides 13–20. For the ...

Related Articles:

3'-O-Formyl-(N-acyl)-2'-deoxyribonucleosides as building units in the synthesis of oligodeoxyribonucleotides

[Smrt, Jiri Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 8 p. 2157 - 2169]

3'-O-Formyl-(N-acyl)-2'-deoxyribonucleosides as building units in the synthesis of oligodeoxyribonucleotides

[Smrt, Jiri Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 8 p. 2157 - 2169]

3'-O-Formyl-(N-acyl)-2'-deoxyribonucleosides as building units in the synthesis of oligodeoxyribonucleotides

[Smrt, Jiri Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 8 p. 2157 - 2169]

3'-O-Formyl-(N-acyl)-2'-deoxyribonucleosides as building units in the synthesis of oligodeoxyribonucleotides

[Smrt, Jiri Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 8 p. 2157 - 2169]

3'-O-Formyl-(N-acyl)-2'-deoxyribonucleosides as building units in the synthesis of oligodeoxyribonucleotides

[Smrt, Jiri Collection of Czechoslovak Chemical Communications, 1982 , vol. 47, # 8 p. 2157 - 2169]

More Articles...