Chemistry–A European Journal

A Useful, Reliable and Safer Protocol for Hydrogenation and the Hydrogenolysis of O??Benzyl Groups: The In Situ Preparation of an Active Pd0/C Catalyst with Well?? …

FX Felpin, E Fouquet

Index: Felpin, Francois-Xavier; Fouquet, Eric Chemistry - A European Journal, 2010 , vol. 16, # 41 p. 12440 - 12445

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Citation Number: 46

Abstract

Abstract A simple, highly reproducible protocol for the hydrogenation of alkenes and alkynes and for the hydrogenolysis of O-benzyl ethers has been developed. The method features the in situ preparation of an active Pd 0/C catalyst from Pd (OAc) 2 and charcoal, in methanol. The mild reaction conditions (25 C) and low catalyst loading required (0.025 mol%), as well as the absence of contamination of the product by palladium residues (< 4 ppb), make this ...