Radical intermediates in the peroxidation of indoles

P Astolfi, L Greci, C Rizzoli, P Sgarabotto…

Index: Astolfi; Greci; Rizzoli; Sgarabotto; Marrosu Journal of the Chemical Society, Perkin Transactions 2, 2001 , # 9 p. 1634 - 1640

Full Text: HTML

Citation Number: 20

Abstract

Results The indoles studied in the present work were 2-alkylindoles (R′= methyl, 5; R′= tert-butyl, 6; R′= phenyl, 7), 1, 2-dialkylindoles (R= R′= methyl, 8; R= ethyl, R′= phenyl, 9)(Scheme 1), 2, 3-dialkylindoles (R= R′= methyl, 14a; R= R′= phenyl 14b; see Scheme 2) and 1-hydroxy-2-phenylindole 16. All indoles were reacted in the presence of oxygen with m-chloroperbenzoic acid and hydrogen peroxide using trichloroacetic acid or calcium ...

Related Articles:

A Combined Experimental and Density Functional Theory Study on the Pd??Mediated Cycloisomerization of o??Alkynylnitrobenzenes–Synthesis of Isatogens and Their …

[Ramana, Chepuri V.; Patel, Pitambar; Vanka, Kumar; Miao, Benchun; Degterev, Alexei European Journal of Organic Chemistry, 2010 , # 31 p. 5955 - 5966]

A one-step synthesis of 2-(2-pyridyl)-3H-indol-3-one N-oxide: is it an efficient spin trap for hydroxyl radical?

[Rosen, Gerald M.; Tsai, Pei; Barth, Eugene D.; Dorey, Gilbert; Casara, Patrick; Spedding, Michael; Halpern, Howard J. Journal of Organic Chemistry, 2000 , vol. 65, # 14 p. 4460 - 4463]

Synthesis and antiplasmodial activity of new indolone N-oxide derivatives

[Nepveu, Francoise; Kim, Sothea; Boyer, Jeremie; Chatriant, Olivier; Ibrahim, Hany; Reybier, Karine; Monje, Marie-Carmen; Chevalley, Severine; Perio, Pierre; Lajoie, Barbora H.; Bouajila, Jalloul; Deharo, Eric; Sauvain, Michel; Tahar, Rachida; Basco, Leonardo; Pantaleo, Antonella; Turini, Francesco; Arese, Paolo; Valentin, Alexis; Thompson, Eloise; Vivas, Livia; Petit, Serge; Nallet, Jean-Pierre Journal of Medicinal Chemistry, 2010 , vol. 53, # 2 p. 699 - 714]

Alkynes from 5-aminoisoxazoles

[Beccalli, Egle M.; Manfredi, Amedea; Marchesini, Alessandro Journal of Organic Chemistry, 1985 , vol. 50, # 13 p. 2372 - 2375]

Alkynes from 5-aminoisoxazoles

[Beccalli, Egle M.; Manfredi, Amedea; Marchesini, Alessandro Journal of Organic Chemistry, 1985 , vol. 50, # 13 p. 2372 - 2375]

More Articles...