Synthesis of N??methyl??3??aza [10] paracyclophane: A rigid analog of phenethylamine

GS Wu, IC Martinelli, CD Btanton…

Index: Wu,G.-S. et al. Journal of Heterocyclic Chemistry, 1977 , vol. 14, p. 11 - 17

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Abstract

Abstract The synthesis of N-methyl-3-aza [10] paracyclophane is reported which represents the first example of this ring system being formed via an acyloin reaction. This 3-aza [10] paraeyclophane ring system behaves physiochemically inbetween the normal [9]-and [10] paracyclophane ring systems. Reductive desulfurization of N-methyl-3-aza [10] paracyclophane-6-ethylene thioketal in ethanol provides a small amount of the title ...