Design and synthesis of some new quinoline-3-carbohydrazone derivatives as potential antimycobacterial agents
…, AV Adhikari, NK Pal, IH Chowdhury
Index: Eswaran, Sumesh; Adhikari, Airody Vasudeva; Pal, Nishith K.; Chowdhury, Imran H. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 1040 - 1044
Full Text: HTML
Citation Number: 61
Abstract
A series of 26 new quinoline derivatives carrying active pharmacophores has been synthesized and evaluated for their in vitro antituberculosis activity against Mycobacterium tuberculosis H37Rv (MTB), Mycobacterium smegmatis (MC2), and Mycobacterium fortuitum following the broth micro dilution assay method. Compounds 13e, 13i, 13k, 14a, 14c, 14i, and 14k exhibited significant minimum inhibition concentrations, when compared with first ...
Related Articles:
[Li, Bryan; Berliner, Martin; Buzon, Richard; Chiu, Charles K.-F.; Colgan, Stephen T.; Kaneko, Takushi; Keene, Nandell; Kissel, William; Le, Tung; Leeman, Kyle R.; Marquez, Brian; Morris, Ronald; Newell, Lisa; Wunderwald, Silke; Witt, Michael; Weaver, John; Zhang, Zhijun; Zhang, Zhongli Journal of Organic Chemistry, 2006 , vol. 71, # 24 p. 9045 - 9050]
[Synthetic Communications, , vol. 18, # 4 p. 441 - 444]