Synthesis and antifungal properties of benzylamines containing boronate esters

…, FJ Baerlocher, SA Westcott

Index: Wynberg, Natalie A.; Leger, Lisa J.; Conrad, Maren L.; Vogels, Christopher M.; Decken, Andreas; Duffy, Stephen J.; Westcott, Stephen A. Canadian Journal of Chemistry, 2005 , vol. 83, # 6-7 p. 661 - 667

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Citation Number: 38

Abstract

Addition of 3-H2NC6H4Bpin (pin= 1, 2-O2C2Me4) to a series of aldehydes and 4-(4, 4, 5, 5- tetramethyl-1, 3, 2-dioxaborolan-2-yl) acetophenone afforded the corresponding benzylideneamines in moderate to high yields. Hydroboration of these imines with catecholborane (HBcat, cat= 1, 2-O2C6H4) at room temperature gives, upon aqueous workup, the corresponding borylamines. An X-ray diffraction study was carried out on ...