Generation and reactions of oxiranyllithiums by use of a flow microreactor system

A Nagaki, E Takizawa, J Yoshida

Index: Nagaki, Aiichiro; Takizawa, Eiji; Yoshida, Jun-Ichi Chemistry - A European Journal, 2010 , vol. 16, # 47 p. 14149 - 14158

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Citation Number: 34

Abstract

Abstract A flow microreactor system consisting of micromixers and microtubes provides an effective reactor for the generation and reactions of aryloxiranyllithiums without decomposition by virtue of short residence time and efficient temperature control. The deprotonation of styrene oxides with sBuLi can be conducted by using the flow microreactor system at− 78 or− 68 C (whereas much lower temperatures (<− 100 C) are needed for the ...

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