Tetrahedron

Room temperature ionic liquid promoted improved and rapid synthesis of 2, 4, 5-triaryl imidazoles from aryl aldehydes and 1, 2-diketones or α-hydroxyketone

SA Siddiqui, UC Narkhede, SS Palimkar, T Daniel…

Index: Siddiqui, Shapi A.; Narkhede, Umesh C.; Palimkar, Sanjay S.; Daniel, Thomas; Lahoti, Rajgopal J.; Srinivasan, Kumar V. Tetrahedron, 2005 , vol. 61, # 14 p. 3539 - 3546

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Citation Number: 262

Abstract

An improved and rapid one-pot synthesis of 2, 4, 5-triaryl imidazoles in a room temperature ionic liquid is described, which does not need any added catalyst. Different ionic liquids based on 1-n-butyl and 1, 3-di-n-butyl imidazolium salts were screened and their efficacy in terms of acidity and polarity have been correlated with yields and reaction period. The one- pot methodology resulting in excellent isolated yields in short reaction times is ...