Synthesis of. gamma.-and. delta.-(1, 3-dithianyl). beta.-keto esters

EC Taylor, JL LaMattina

Index: Taylor,E.C.; LaMattina,J.L. Journal of Organic Chemistry, 1978 , vol. 43, p. 1200 - 1204

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Citation Number: 23

Abstract

Previous papers from this laboratory have described an unambiguous approach to the synthesis of 6-substituted pteridines by guanidine cyclization of 2-amino-3-cyano (or alkoxycarbonyl) pyrazines suitably substituted at position 5. These latter critical intermediates were prepared in turn by cyclization of aminomalononitrile (or esters of a- aminocyanoacetic acid) with an a-ketoaldoxime, followed by deoxygenation of the ...