Tetrahedron

Enantioselective synthesis of N-heterocycles via intramolecular Pd (0)-catalysed allylic amination

B Olszewska, B Kryczka, A Zawisza

Index: Olszewska, Beata; Kryczka, Boguslaw; Zawisza, Anna Tetrahedron, 2013 , vol. 69, # 46 p. 9551 - 9556

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Citation Number: 5

Abstract

Abstract An efficient and stereoselective synthesis of pyrrolidine-, piperidine-, and azepane- type N-heterocycles is described by the intramolecular Pd (0)-catalysed cyclisation of amino allylic carbonates. The use of chiral ligands gave the corresponding heterocyclic derivatives having er values that were from moderate to good.

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