Chemistry–A European Journal

A High??Yielding Modular Access to the Lamellarins: Synthesis of Lamellarin G Trimethyl Ether, Lamellarin η and Dihydrolamellarin η

D Imbri, J Tauber, T Opatz

Index: Imbri, Dennis; Tauber, Johannes; Opatz, Till Chemistry - A European Journal, 2013 , vol. 19, # 45 p. 15080 - 15083

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Citation Number: 11

Abstract

Lamellarins are polyaromatic marine alkaloids sharing a common condensed pentacyclic skeleton with a saturated (Figure1, type1a) or unsaturated (type1b) isoquinoline moiety. In rarer cases, the scaffold is limited to an unfused 3, 4-diarylpyrrole core (type 2). The structural diversity within the lamellarin family largely originates from their varying oxygenation and O-substitution pattern.[1] Since their discovery by Faulkner etal. in 1985,[ ...