Carbon-carbon bond formation in regio-and stereoselective palladium-catalyzed cyclization of allene-substituted conjugated dienes

J Löfstedt, J Franzén, JE Bäckvall

Index: Loefstedt, Joakim; Franzen, Johan; Baeckvall, Jan-E. Journal of Organic Chemistry, 2001 , vol. 66, # 24 p. 8015 - 8025

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Citation Number: 39

Abstract

Regio-and stereoselective palladium-catalyzed reactions of allene-substituted 1, 3-dienes 1 in acetic acid at room temperature lead to cyclization with formation of a carbon-carbon bond between the middle carbon of the allene and the terminal carbon of the 1, 3-diene. Two different types of reactions, both that constitute 1, 4-carboacetoxylations of the 1, 3-diene, have been developed. In one of the reactions, Pd (II) catalyzes the oxidation of 1 to ...