Ketone synthesis under neutral conditions. Cu (I) diphenylphosphinate-mediated, palladium-catalyzed coupling of thiol esters and organostannanes
R Wittenberg, J Srogl, M Egi, LS Liebeskind
Index: Wittenberg, Ruediger; Srogl, Jiri; Egi, Masahiro; Liebeskind, Lanny S. Organic Letters, 2003 , vol. 5, # 17 p. 3033 - 3035
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Citation Number: 111
Abstract
A versatile approach to ketone synthesis is described. The reaction relies on the palladium- catalyzed, copper diphenylphosphinate-mediated coupling of thiol esters with organostannanes under neutral reaction conditions. This reaction complements the previously described coupling of thiol esters with boronic acids that used dual thiophilic- borophilic activation methodology.
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