Palladium??and Solvent??Free Synthesis of Ynones by Copper (I)??Catalyzed Acylation of Terminal Alkynes with Acyl Chlorides under Aerobic Conditions

E Mohammadi, B Movassagh…

Index: Mohammadi, Elmira; Movassagh, Barahman; Navidi, Mozhgan Helvetica Chimica Acta, 2014 , vol. 97, # 1 p. 70 - 75

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Citation Number: 10

Abstract

Introduction. – Among several protocols for the synthesis of ynones [1–3], the reaction of acyl chlorides with alkynyl organometallic reagents, based on copper [4], zinc [5], tin [6], silver [7], lithium [8], and silicon [9], is arguably one of the most versatile and efficient methods. Recently, the coupling reaction of terminal alkynes and acyl chlorides catalyzed by Pd catalysts has received much attention [10]; but, on the other hand, efficient Pd-free systems would ...

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