A versatile synthetic approach to grandisol monoterpene pheromone

YT Han, NJ Kim, JW Jung, H Yun, S Lee…

Index: Han, Young Taek; Kim, Nam-Jung; Jung, Jong-Wha; Yun, Hwayoung; Lee, Sujin; Suh, Young-Ger Archives of Pharmacal Research, 2011 , vol. 34, # 9 p. 1437 - 1442

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Citation Number: 3

Abstract

Abstract A versatile and efficient synthetic procedure for the grandisol pheromone library has been established. The key feature of our synthesis involves a versatile and highly regioselective Pd (0)-catalyzed intramolecular allylic alkylation for the key cyclobutane skeleton of grandisol. In this connection, the concise synthesis of (±)-grandisol as well as mechanism study of Pd (0)-catalyzed regioselective cyclization as a key reaction have ...