Fast microwave-assisted oxidation of 1, 4-dihydropyridines with FeCl3. SiO2

…, MA Khalilzadeh, E Alaee, M Tajbakhsh

Index: Hosseini, Abolfazl; Halvagar, Mohammad Reza; Khalilzadeh, Mohammad Ali; Alaee, Ehsan; Tajbakhsh, Mahmood Journal of Chemical Research, 2005 , # 1 p. 48 - 49

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Abstract

The oxidation of Hantzsch 1,4-dihydropyridines (1,4-DHPs) to the corresponding pyridines has attracted considerable attention since they have been extensively utilised as the analogues of NAD(P)H coenzymes to study the mechanism and synthetic potential of various redox processes.1 In addition, some 1,4-DHP based antihypertensive drugs (Ca2+ channel blockers) have been used in the treatment of various cardiovascular disorders.2 ...