The Journal of Organic Chemistry

Preparation of fluoro amines by the reaction of aziridines with hydrogen fluoride in pyridine solution

TN Wade

Index: Wade, Tamsir N. Journal of Organic Chemistry, 1980 , vol. 45, # 26 p. 5328 - 5333

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Citation Number: 59

Abstract

Hydrogen fluoride combines regiospecifcally with aziridines (1) to give 2-fluor0 amines (6) in good yields. Fluorine attack is in all cases completely directed to the most substituted ring carbon or to the benzylic carbon. The results, for benzylic aziridines, are consistent with an