Tetrahedron Letters

Cleavage and oligomerization of malondialdehyde under physiological conditions

A Gómez-Sánchez, I Hermosín, I Maya

Index: Gomez-Sanchez, Antonio; Hermosin, Isidro; Maya, Ines Tetrahedron Letters, 1990 , vol. 31, # 28 p. 4077 - 4080

Full Text: HTML

Citation Number: 32

Abstract

Abstract Malondialdehyde slowly oligomerizes in aqueous solution at pH 5-7 and room temperature. Cleavage of the dialdehyde also takes place under these conditions yielding ethanal, which further reacts with the excess of malondialdehyde to yield 2, 4- dihydroxymethylene-3-methylglutaraldehyde.