Cyclization of enediyne radical cations through chemical, photochemical, and electrochemical oxidation: The role of state symmetry

D Ramkumar, M Kalpana, B Varghese…

Index: Ramkumar, Dhruva; Kalpana, Mahadevan; Varghese, Babu; Sankararaman, Sethuraman; Jagadeesh, Mavinahalli N.; Chandrasekhar, Jayaraman Journal of Organic Chemistry, 1996 , vol. 61, # 6 p. 2247 - 2250

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Citation Number: 51

Abstract

Enediyne chemistry has gained prominence in recent years in view of the presence of the moiety in several naturally occurring antitumor antibiotics. 1 Thermally activated cycloaromatization to form 1, 4-dehydrobenzene diradical (Bergman cyclization) is of special interest as the process has been implicated in the DNA-cleaving ability of many natural products and synthetic analogues. 2 Photoinduced dimerization, 3 cis-trans isomerization, ...