Topics in Current Chemistry 2018-01-22

Analysis of US FDA-Approved Drugs Containing Sulfur Atoms

Kevin A. Scott, Jon T. Njardarson

Index: 10.1007/s41061-018-0184-5

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Abstract

In this review, we discuss all sulfur-containing FDA-approved drugs and their structures. The second section of the review is dedicated to structural analysis and is divided into 14 subsections, each focusing on one type of sulfur-containing moiety. A concise graphical representation of each class features drugs that are organized on the basis of structural similarity, evolutionary relevance, and medical indication. This review offers a unique and comprehensive overview of the structural features of all sulfur-containing FDA-approved drugs to date.

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