Synthesis and evaluation of (2-phenethyl-2H-1, 2, 3-triazol-4-yl)(phenyl) methanones as Kv1. 5 channel blockers for the treatment of atrial fibrillation

…, K Coburn, W Lee, N Fairweather, A Fluxe, S Wu…

Index: Blass, Benjamin E.; Coburn, Keith; Lee, Wenlin; Fairweather, Neil; Fluxe, Andrew; Wu, Shengde; Janusz, John M.; Murawsky, Michael; Fadayel, Gina M.; Fang, Bin; Hare, Michelle; Ridgeway, Jim; White, Ron; Jackson, Chris; Djandjighian, Laurent; Hedges, Richard; Wireko, Fred C.; Ritter, Amanda L. Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 17 p. 4629 - 4632

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Citation Number: 20

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A series of novel (2-phenethyl-2H-1,2,3-triazol-4-yl)(phenyl)methanones were prepared and examined for utility as Kv1.5 channel blockers for the treatment of atrial fibrillation. ... A series of novel (2-phenethyl-2H-1,2,3-triazol-4-yl)(phenyl)methanones were prepared and examined for ...

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