5-Acetyl-2-arylbenzimidazoles as antiviral agents. Part 4

…, G Sanna, P Farci, ME Marongiu, P La Colla

Index: Vitale, Gabriella; Corona, Paola; Loriga, Mario; Carta, Antonio; Paglietti, Giuseppe; Giliberti, Gabriele; Sanna, Giuseppina; Farci, Pamela; Marongiu, Maria Elena; La Colla, Paolo European Journal of Medicinal Chemistry, 2012 , vol. 53, p. 83 - 97

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Citation Number: 14

Abstract

Within a project aimed at discovering new Flaviviridae inhibitors, new variously substituted 2- phenylbenzimidazoles were synthesized and evaluated in cell-based assays for cytotoxicity and antiviral activity against viruses representatives of the three genera of the Flaviviridae family, ie: Pestivirus (BVDV), Flavivirus (YFV) and Hepacivirus (HCV). Title compounds were also tested against RNA viruses representative of other single-stranded, positive-sense ( ...

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